AnnoTree

AnnoTree is a web tool for visualization of genome annotations across large phylogenetic trees. AnnoTree version 1.1 includes KEGG, Pfam and TIGRFAM annotations for over 27,000 bacterial and 1500 archaeal genomes. Phylogenetic and taxonomy information is derived from the GTDB database (Release 03-RS86).

Future releases will include additional types of functional annotations and expand the phylogenomic framework to Eukaryotes.

Features


Painted phylogenies in three steps

(1) Highlight taxonomies of interest with the annotation or taxonomy search option; (2) Zoom to any level of detail; (3) Download a publication-quality SVG or a NEWICK file

Reductive Dehalogenase
Summary distribution of reductive dehalogenase

A concise view of taxonomic distribution

Instantly summarize the taxonomic distribution of Pfam protein domains, KEGG orthologs, or TIGRFAM families across all phylogenetic levels

Details, down to the last residue

Examine and download every annotation confidence score and protein sequence directly from the interface

Download CSV through pop up

Cite us


Kerrin Mendler, Han Chen, Donovan H Parks, Briallen Lobb, Laura A Hug, Andrew C Doxey. (2019) AnnoTree: visualization and exploration of a functionally annotated microbial tree of life. Nucleic Acids Research gkz246; doi: https://doi.org/10.1093/nar/gkz246

Team


AnnoTree is developed by the Doxey Lab at the University of Waterloo.

  • Han Chen (core developer)
  • Kerrin Mendler (core developer)
  • Donovan Parks (GTDB genomic data and TOL)
  • Briallen Lobb (statistics, phylogenomics)
  • Laura Hug (phylogenomics, case studies, TOL)
  • Andrew Doxey (tool conception/design)